Application

Western Blotting Analysis: 2.0 µg/mL from a representative lot detected CORO1A in 10 µg of NIH3T3 cell lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected CORO1A in human cerebral cortex issue.

Research CategoryNeuroscience

Research Sub CategoryDevelopmental Signaling

Detect Coronin using this mouse monoclonal antibody, Anti-CORO1A Antibody, clone 2E11.2 validated for use in western blotting & ICC.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Coronin-1A (CORO1A) is also called Coronin-like protein A (Clipin-A), Coronin-like protein p57, and Tryptophan aspartate-containing coat protein (TACO). CORO1A is likely a critical cytoskeleton component in highly motile cells that is involved in invagination and forming protrusions of the plasma membrane to facilitate cell movement. CORO1A is expressed in brain, thymus, spleen, bone marrow and lymph nodes.

Immunogen

GST-tagged recombinant protein corresponding to the C-terminus of human CORO1A.

Epitope: C-terminus

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Protein G Purified

Format: Purified

Quality

Evaluated by Western Blotting in Raji cell lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected CORO1A in 10 µg of Raji cell lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~51 kDa observed